Synaptogenix, Inc., an emerging biopharmaceutical company developing regenerative therapeutics for neurodegenerative disorders, commented on the positive Phase 3 trial results for Lecanemab announced last night by Eisai and Biogen.
Dr. Daniel Alkon, President and Chief Scientific Officer of Synaptogenix, stated, “We continue to welcome the significant commitment that Biogen and Eisai are making towards developing a new treatment option for Alzheimer’s disease (AD). Synaptogenix shares the same commitment to treat AD, although the focus of Synaptogenix resources are toward the actual restoration of function and disease reversal, versus a singular focus on slowing the disease’s rate of clinical decline. The Synaptogenix lead compound Bryostatin-1, now in an extended clinical trial, is believed to work on regeneration of brain wiring (synaptic networks), in addition to a reduction of amyloid that is targeted by the Biogen/Eisai compound. Regeneration of brain wiring may result in actual improvement of patients’ cognitive performance, not just slowing of cognitive decline – as we reported for exploratory analyses of previous Bryostatin trial results in the Journal of Alzheimer’s Disease a few months ago. We believe that innovative, potentially restorative drug targets will add to the potential therapeutic benefits that FDA-approved medications must eventually offer to the millions of AD patients. We are excited to present our Phase 2 data during the fourth quarter of this year.”
Also Read: CP Kelco Partners With Exopolymer to Bring Functional Biopolymers to Market
Synaptogenix is a clinical-stage biopharmaceutical company that has historically worked to develop novel therapies for neurodegenerative diseases. Synaptogenix has conducted clinical and preclinical studies of its lead therapeutic candidate, Bryostatin-1, in Alzheimer’s disease. Preclinical studies have also demonstrated Bryostatin’s regenerative mechanisms of action for the rare disease, Fragile X syndrome, and for other neurodegenerative disorders such as multiple sclerosis, stroke, and traumatic brain injury. The U.S. Food and Drug Administration has granted Orphan Drug Designation to Synaptogenix for Bryostatin-1 as a treatment for Fragile X syndrome. Bryostatin-1 has already undergone testing in more than 1,500 people in cancer studies, thus creating a large safety data base that will further inform clinical trial designs. Additional information about Synaptogenix, Inc.