Thursday, March 28, 2024

USP Cannabis Expert Panel Identifies Public Health Issues Associated with Delta-8 THC Products & Offers Recommendations

The United States Pharmacopeia (USP) has drafted a commentary, It’s time to hold cannabinoid products to the highest standard: USP Cannabis Panel statement on Delta8-THC, to provide recommendations for addressing the potential health risks that delta-8 tetrahydrocannabinol (THC)-containing products pose to the public. In tandem, ASTM International also drafted a technical paper, Delta-8 Tetrahydrocannabinol and the Need to Develop Standards to Protect Safety of Consumers, outlining possible concerns associated with the cannabinoid. The two standards development organizations focused on the science and urge manufacturers and laboratories to do more research into the minor cannabinoids in order to help ensure public safety.

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“The fact of the matter is that little is known about the products labeled as containing delta-8, so much so that the FDA and CDC have both released advisories about the products. Depending on how the products are produced, unknown impurities may be introduced, including minor and synthetic cannabinoid compounds that are not naturally occurring in cannabis,” explains Dr. Ikhlas Khan, Chairman of USP’s Expert Panel on cannabis.

“Products containing delta-8 can be found in gas stations, convenience stores, and are readily available over the internet without any warnings or safeguards, providing consumers with a false sense of security that these products are safe for consumption,” notes David Vaillencourt, CEO of The GMP Collective and ASTM International member. “With many other synthetically derived cannabinoids continuing to emerge in the marketplace, quality-based approaches should be used to address this issue.”

Synthetically derived cannabinoids are not necessarily inherently unsafe if they are quality controlled and shown to be safe. By using public quality standards, we can help in controlling the quality of the products and set appropriate limits for impurities. USP has been using data-driven approaches to quality standards development for over two hundred years and is well equipped to address this growing health concern in a proactive, scientific process,” said Dr. Nandakumara Sarma, Director of Dietary Supplements and Herbal Medicines for USP.

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