Friday, April 26, 2024

BostonGene and Little Warrior Foundation Collaborate to Bring Novel Liquid Biopsy Solutions into Clinical Practice

BostonGene announced a collaboration with Little Warrior Foundation to drive the discovery, validation, and implementation of novel liquid biopsy solutions into sarcoma clinical practice.

Little Warrior Foundation was founded in 2020 with a simple mission to fund and find a lasting cure for childhood cancer, specifically focusing on Ewing Sarcoma. Funds the foundation raises are granted to researchers and institutions developing high-potential therapies and novel solutions for pediatric applications.

Sarcomas are malignant tumors originating in connective and supportive tissue and are incredibly diverse at the histological and molecular levels. Thus, in sarcomas, clinical decision-making often relies on the molecular features of each unique tumor. Further, sarcomas are fusion-rich, with various fusions as known drivers of myriad sarcomas, highlighting the importance of RNA-based analysis in sarcomas.

Broad liquid biopsy panels have limited applicability for individual cancer types due to the unique molecular landscape of each cancer type; therefore, Little Warrior Foundation has partnered with BostonGene to develop sarcoma-specific cfDNA and cfRNA liquid biopsy assays to increase the sensitivity and accuracy of detecting sarcoma-related molecular alterations and fusions.

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“Our partnership with BostonGene enables us to accelerate research and development efforts by identifying novel solutions for patients with Ewing Sarcoma and related sarcomas,” said Piero Spada, President and Co-Founder, Little Warrior Foundation. “We expect this collaboration to provide physicians with the necessary tools to monitor for relapse and reoccurrence in a more efficient manner, ultimately impacting integral clinical decisions for patients.”

“We share a commitment with Little Warrior Foundation to develop and implement breakthrough solutions for patients with myriad sarcomas,” said Nathan Fowler, MD, Chief Medical Officer at BostonGene. “BostonGene’s advanced sequencing and analytics will propel the development of more effective treatment strategies, ultimately positively impacting pediatric and adult patients.”

BostonGene’s mission is to power healthcare’s transition to personalized medicine using AI-based molecular and immune profiling to improve the standard of care, accelerate research, and reduce overall cost of cancer care. BostonGene’s tests reveal key drivers of each tumor, including immune microenvironment properties, actionable mutations, biomarkers of response to diverse therapies, and recommended therapies.

SOURCE: Busineswwire

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