Tuesday, November 5, 2024

Zymo Research Makes Strategic Investment in Star Array to Develop an Automated Nucleic Acid Extraction/Superfast PCR Platform for the POCT Market

Zymo Research and Star Array announced Zymo Research’s strategic investment to acquire an interest in Star Array, a privately owned, biomedical technology company based in Singapore. The investment allows Zymo Research and Star Array to combine Zymo Research’s nucleic acid purification and assay technologies with Star Array’s engineering and automation expertise to expand into emerging For Research Use Only (FRUO) and diagnostic markets including Point-of-Care testing (POCT).

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Star Array’s focus has been on the development of an automated (cassette-based) nucleic acid purification system coupled with its superfast nucleic acid amplification technology. It manufactures and markets various genetic analyzers including its premier product, XDive™, a superfast qPCR platform, with related kits and software. During the COVID-19 outbreak, Star Array developed a test for SARS-CoV-2 detection utilizing its XDive™ system. The entire process from sample-to-answer takes less than 45 minutes and the system can be used in any clinical environment. Star Array is currently working through the Emergency Use Authorization (EUA) process with the U.S. Food and Drug Administration (FDA) through the National Institutes of Health (NIH) Rapid Acceleration of Diagnostics (RADx®) program.

Zymo Research, since its inception in 1994, is well known for its DNA/RNA extraction and assay technologies. Its goal has been to develop more efficient sample collection kits and devices that simplify and reduce the time needed to isolate nucleic acids in the laboratory. Zymo Research will be partnering with Star Array to develop ready-made cassettes containing the necessary reagents for Star Array’s COVID-19 test kit as well as future POCT.

“Star Array’s powerful PCR instrumentation places them at the forefront of PCR technology with their XDive™ PCR system that can complete a typical 40-cycle multiplex qPCR run in 5-7 minutes. When coupled with Star Array’s system, Zymo Research’s DNA/RNA purification reagents and nucleic acid-based assays will facilitate a straightforward Sample-In/Answer-Out workflow. Through our investment in Star Array we will develop products targeting POCT in the global marketplace,” said Marc Van Eden, Vice President of Business Development at Zymo Research.

“Zymo Research and Star Array have both built businesses at the intersection of science and technology and we share a vision of ultrafast PCR technology that will enable POC PCR tests to be analyzed in just minutes in doctor’s offices, laboratories, and hospitals. Together we strive to build even more POCT products in the future,” said Dr. Yanhui Liu, Vice President of Star Array Pte. Ltd.

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