Transgene , a biotech company that designs and develops virus-based immunotherapeutics against cancer, will host an R&D event for investors and research analysts in Paris.
Hedi Ben Brahim, CEO of Transgene, commenting on the Company’s R&D Day said: “Today’s event will highlight our world leading scientific and translational expertise which has allowed us to design the next generation of virus-based immunotherapies against cancer. We will provide updated data on the previous Phase Ib/II trial of TG4001 and avelumab in HPV16-positive cancer patients and the updated clinical follow up of patients enrolled in the two Phase I trials with TG4050, which are all positive and consistent with previous findings. In addition, we will outline the progress we have made with our exciting Invir.IO™ platform, which via intravenous administration could significantly broaden the potential of oncolytic viral therapies. I would like to thank our expert speakers for participating in our R&D event which I am confident will demonstrate that Transgene remains on track to deliver a number of important value adding clinical milestones over the next 18 months.”
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The event, which features presentations by leading clinicians and scientists from around the world, as well as key members of the Transgene management team, provides insights on:
– TG4001, with updated data from the previous trial (Phase Ib/II) evaluating the combination of TG4001 and avelumab in HPV16-positive cancers;
– TG4050, with updated follow up data from the two Phase I trials in ovarian cancer and head and neck cancer;
– The progress of the Invir.IO™ platform, with a focus on a novel oncolytic virus vectorizing human IL-12 that has been designed to be administered intravenously.
The R&D Day’s key speakers, which also includes key members of Transgene’s management team, are:
- Jean-Pierre Delord, MD, PhD, General Manager of IUCT Oncopole of Toulouse, will present: “TG4001 – a HPV16 Therapeutic vaccine in Phase II”.
- Christian Ottensmeier, MD, PhD, FRCP, Professor of Immuno-oncology at the University of Liverpool, The Clatterbridge Cancer Center NHS Foundation Trust, will present: “From the design of the myvac® platform to first immunological and clinical readouts, Update on the head and neck trial of TG4050”.
- Matthew Block, MD, PhD, Medical oncologist at the Mayo Clinic, will present: “TG4050, a personalized therapeutic vaccine in the treatment of ovarian cancer”.
- Adel Samson, MD, PhD, Clinical Associate Professor, CRUK Clinician Scientist and Honorary Medical Oncologist from the University of Leeds, will present: “Assessing novel routes of administration (IV or locoregional route) with TG6002”.
- Pedro Romero, MD, Chief Editor of the JITC and Deputy scientific managing director of the Lausanne Branch of the Ludwig Institute for Cancer Research, will present: “Opportunities in the immuno-oncology field”.