Parse Biosciences , a leading provider of affordable and scalable single cell sequencing solutions, announced the availability of Evercode™ TCR and Gene Capture solutions. These new solutions will expand the Parse Biosciences portfolio to address larger-scale applications and immunoprofiling analysis.
Evercode TCR offers researchers the ability to profile T cell receptors (TCRs) alongside whole transcriptomes on single cells at scale. While the diversity of possible TCRs is enormous, the poor performance of existing tools has limited the ability to capture this complexity at high resolution. Evercode TCR will allow researchers to measure full-length transcriptomes and equivalent TCR sequences, both alpha and beta chains, in up to 1 million cells. Combining TCR sequences with gene expression at this scale makes it possible to track TCR clonotypes in different T cell subtypes and activation states to understand the immune repertoire with exceptional resolution.
Additionally, Parse announced the launch of Gene Capture, a solution to reduce sequencing needs in larger studies. Gene Capture focuses on sequencing the most relevant genes, making it possible to efficiently scale projects to millions of cells and hundreds of samples. The solution allows researchers to enrich hundreds or thousands of genes, which requires 10 times less sequencing. Researchers can request a pre-built panel of approximately 1,000 immunology-relevant genes, the Immune1000, or design a panel unique to their specific needs.
“We see a growing need to support larger single cell RNA sequencing studies. Biology is complex, and fully capturing this complexity requires robust studies across multiple samples, time points, and many individual cells,” notes Parse co-founder and CEO Alex Rosenberg, Ph.D. “Parse’s technology has already brought unprecedented scale to the market, and these new tools will expand these capabilities as they unlock new applications, both in the research and translation space.”
Charles Roco, Ph.D., co-founder and CTO of Parse, will present the capabilities of Parse’s Evercode TCR and Gene Capture products at the AGBT general meeting this week in his session titled “ Broadening Access to Scalable Single Cell Sequencing ”. access to scalable single cell sequencing) on Wednesday, February 8, at 3:35 pm, in the Grand Ballroom .
SOURCE: Businesswire