GenScript Biotech Corporation, one of the world’s leading providers of life-science research tools and services, and Multiply Labs, a robotics company developing industry-leading automated manufacturing systems to produce individualized drugs, announced a strategic partnership around the automation of the cell isolation phase of cell therapy manufacturing, reducing the complexity of this laborious process.
Cell isolation using immunomagnetic beads is a critical industry-standard process in cell therapy manufacturing. However, the current method of performing this task manually is complex and time-consuming. In addition to the sensitivity of cells, intricate process and precision required, the approach requires manually handling, connecting and double-checking complex closed-system consumable kits.
By utilizing Multiply Labs’ cell therapy robotic cluster and GenScript’s GMP-grade CytoSinct 1000 cell isolation solution, capable of isolating up to 120X10^9 total cells within a single hour, this collaboration will introduce the first fully automated solution for bead-based cell isolation. Importantly, this automation technology will not require cell therapy manufacturers to make substantial modifications to their original manufacturing processes.
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This advancement promises to mitigate the risk of human error while simultaneously boosting cell therapy output. Once this part of the process can be run without human intervention, manufacturing operators and process scientists will be free to oversee the production of more therapies at once, without being tied down in the delicate, tedious, and mission-critical manual tasks involved in the traditional manufacturing process. Automation in this deeply time-consuming area of the process will therefore drive significant benefits around efficiency, and ultimately support the scalability of cell therapies.
“Our collaboration with Multiply Labs marks a significant advancement in personalized medicine and the potential impact of cell therapies,” said Ray Chen, PhD, President of Life Science Group at GenScript. “By automating our industry-leading solution, we can dramatically increase productivity and scale operations to unprecedented levels.”
“We’re thrilled to partner with GenScript to enhance a critical aspect of the cell therapy process through automation,” said Fred Parietti, PhD, Co-Founder and CEO of Multiply Labs. “This collaboration advances our goal of a fully automated, end-to-end therapy manufacturing process, reducing costs and expanding patient access to life-changing treatments.”
SOURCE: PRNewswire