Dovetail Genomics announces the Dovetail® AssemblyLink™ Assay, a transformative genomics tool designed to redefine the standards of speed and quality in genomic assembly. Built upon Dovetail’s core LinkPrep™ Technology, the AssemblyLink Assay streamlines the genome assembly process by rapidly generating Hi-C-like libraries. Based on its compelling features and benefits, it is expected to be the kit of choice for genome scaffolding in high-throughput biodiversity labs running a wide variety of species.
Distinct from traditional Hi-C methods, which typically require two to three days to progress from sample to sequencing library, the AssemblyLink Assay cuts this workflow down to a single day. Additionally, it delivers highly uniform sequence coverage facilitating critical variant phasing that enables the production of true haplotype-resolved assemblies. Moreover, this unique attribute offers an easier path to chromosome-scale assembly of higher ploidy genomes. This advanced capability set ensures the most accurate genome representations for species of interest, enabling researchers to compile genomes of the highest quality more rapidly.
“We are proud to be equipping researchers with advanced tools crucial for their work during this critical period of biodiversity loss.” commented Matt Easterday, CEO of Dovetail Genomics, part of Cantata Bio LLC. “AssemblyLink accelerates the research process and significantly improves the accuracy of the genomic data, facilitating deeper insights into genetic diversity and aiding in the preservation of the genetic heritage of numerous species.”
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Today, consortia are charged with the ambitious goal of preserving the earth’s genetic biodiversity in the face of rapid species extinction via efforts to catalog thousands of species. The AssemblyLink Assay significantly bolsters these efforts by empowering researchers and consortia to achieve faster, more informative assemblies, enhancing critical conservation work. The development of the AssemblyLink Assay underscores Dovetail Genomics’ unwavering commitment to innovation in the genome assembly sector and its continued support of the critical mission of global consortia. Through various research collaborations and an early access program, Dovetail Genomics has partnered with many leading institutions.
“We’re thrilled to onboard the Dovetail AssemblyLink kit.” Remarked Dr. Adrianne Doran, Scientific Officer of The Minderoo OceanOmics Centre at UWA. “We are using Dovetail Hi-C preps to scaffold whole genome assemblies of marine vertebrate species, as we create a comprehensive library of high-quality reference genomes. The refined workflow will decrease hands-on time in the lab and increase sequencing throughput. The reduced input requirements from fresh frozen animal tissue means we can now tackle even the smallest specimens without compromising sequencing quality or complexity.”
Furthermore, Dr. Meiyeh Jade Lu, Core Manager, Biodiversity Research Center, Academia Sinica shared “We are pleased to be among the early sites piloting the Dovetail AssemblyLink Kit in our laboratory. The process of the library preparations is smooth, and the new tagmentation chemistry renders the extent of chromatin digestion more controllable. We are very excited about the scaling potential that the assay unlocks due to its rapid and less tedious workflow.”
“We are very excited by the capabilities of the AssemblyLink Kit. It takes just one day to go from sample preparation to sequencing for a novel de novo assembly or for high-resolution 3D genomic interactions. This efficiency will have a great impact, cutting down the process from three days to one without compromising on deliverables.” asserted Dhanya Sooraj, Senior Scientist – Innovation and Development at the Australian Genome Research Facility (AGRF). “At the Australian Genome Research Facility, where we strive to provide premium customer services, we can’t wait to test it further.”
SOURCE: PRNewswire