Curative Biotechnology, Inc., a development-stage biomedical company focused on novel treatments for rare diseases and conditions, announced today a Cooperative Research and Development Agreement (CRADA) with the National Eye Institute (NEI), a part of the National Institutes of Health (NIH).
Under a Cooperative Research and Development Agreement (CRADA), the National Eye Institute and Curative Biotechnology, Inc. will collaborate to evaluate Curative‘s proprietary ocular metformin formulation in clinical studies for the treatment of intermediate and late-stage Age-Related Macular Degeneration (AMD) disease.
TITLE OF CRADA: Clinical Evaluation of Curative Biotechnology,
Inc.’s Proprietary Ocular Metformin Formulation
PHS IC: National Eye Institute
IC Principal Investigator: Emily Chew, M.D.
Collaborator: Curative Biotechnology, Inc.
Collaborator Principal Investigator Steering committee lead representative Dr. Catherine Sohn
TERM OF CRADA: Three (3) years from the Effective Date.
About Dr. Emily Chew
Emily Y. Chew, M.D. is the Director of the Division of Epidemiology and Clinical Applications (DECA) at the National Eye Institute, the National Institutes of Health in Bethesda, Maryland. She is also the Chief of the Clinical Trials Branch in the division. Her research interest includes phase I/II clinical trials and epidemiologic studies in retinovascular diseases such as age-related macular degeneration, diabetic retinopathy, and other ocular diseases. She is the author of more than 200 research articles based on her studies of retinal disease.
About Macular Degeneration
Numerous diseases cause degeneration of the macular tissue in the retina resulting in vision loss or blindness. Age-related macular degeneration (AMD) is a leading cause of vision loss and blindness in the United States and world-wide. As AMD advances through early to intermediate and late stage (Geographic Atrophy, “GA”) progressive degeneration of macular cells may lead to loss of central vision in one or both eyes. There is no cure for AMD and currently very little that can be done to slow its progression. Potential treatments, such as the metformin therapy proposed under this CRADA study, are being tested to address the unmet need for AMD therapies and possibly other retinal degenerative disease.