nRichDX and OraSure Technologies, Inc., have advanced a commercial collaboration to validate and co-promote their products for researchers developing liquid biopsy applications using first-void urine samples. Notably, first-void urine is enriched in biomarkers suitable for molecular analysis in applications such as sexually-transmitted infections, human papillomavirus, and early stage cancer.
The companies’ products are highly complementary. The innovative, patented Colli-Pee sample collection and preservation device, made by OraSure’s subsidiary Novosanis, is designed to hygienically collect a consistent, volumetric first-void urine sample, and preserve the cell-free nucleic acid (cfDNA, including circulating cell-free tumor DNA, and cfRNA) with its proprietary UAS reagent. nRichDX’s patented Revolution Sample Prep System is the only IVD-labeled, cfDNA sample prep system that can process up to 20 mL of urine in a single extraction.
Together, the Colli-Pee first-void urine collection device with UAS preservative, combined with the nRichDx Revolution System, a semi-automated cfDNA extraction platform, offers a seamless and efficient workflow for large-scale studies requiring urine sample collection, preservation, handling and extraction for downstream processing.
“nRichDX is pleased to collaborate with OraSure to provide researchers and clinicians solutions to deliver the highest yields of highly pure cfDNA and ctDNA from urine,” said William Curtis, CEO of nRichDX. “Liquid biopsy test developers are looking forward to the creation of highly sensitive assays from non-invasive urine samples. The unique Revolution System, together with the innovative Colli-Pee device, delivers unmatched yields of cfDNA and ctDNA from urine” he said.
“First-void urine collection is convenient for patients and provides important insight into the state of their health,” said Kathleen Weber, Chief Product Officer for OraSure. “We are excited about this collaboration, which utilizes the Colli-Pee device for first-void urine collection and preservation of important biomarkers that can be extracted with the nRichDx Revolution System. We look forward to the possibilities that higher DNA yields can enable as researchers look for ways to use first-void urine as a more accessible, non-invasive liquid biopsy sample type to expand the potential for global screening, detection, and monitoring of cancers and other medical conditions.”
SOURCE: PR Newswire